A collaborative study with Yuta Yamamoto of Wakayama Medical University, has revealed that HYA (10-hydroxy-cis-12-octadecenoic acid), a metabolite produced by gut bacteria, suppresses postprandial hyperglycemia (a rapid spike in blood glucose levels after eating) in a type 1 diabetes rat model.
These findings suggest that HYA may offer a new therapeutic approach for patients with type 1 diabetes suffering from postprandial hyperglycemia.
The results of this study have been published online in the journal Acta Diabetologica.
Reference
Yamamoto, Y., Narumi, K., Yamagishi, N. et al. HYA ameliorated postprandial hyperglycemia in type 1 diabetes model rats with bolus insulin treatment. Acta Diabetologica (2025).
https://doi.org/10.1007/s00592-025-02459-6
